Monthly Archives: July 2017

A New Review of Embryogenesis Explained

The review is by:

Dr. Palmiro Poltronieri
Editor-in-Chief, Challenges
National Research Council of Italy,
AgroFood Department,
Institute of Sciences of Food Productions
via Monteroni km 7
73100 Lecce, Italy

“The model discussed by the authors is based on a simple, unifying idea that differentiation waves, based on cell cytoskeleton, i.e., contraction and expansion of the network of microfilaments and microtubules, is at the basis of mechano-transduction signalling, that brings transcription factors to regulate chromatin into specific cell-stage differentiation states, based on regulons, i.e., the wholeness of opened DNA regions and inaccessible DNA regions. Thus, from determination of a cell’s fate, i.e., signaling to advancement of process, to differentiation state, i.e., new transcriptional program and reprogramming of active regulons, clusters of cells thus divide, mature and form the various cell type component tissues of the developing embryo.”

And my favourite part:

“Overall, the book is a great book, documenting with images, schematic reproductions and drawings the embryo development, showing parallelisms, universal processes and the peculiarities of various vertebrates and invertebrates.”

You can read the full open access review here: