The review is by:
Dr. Palmiro Poltronieri
National Research Council of Italy,
Institute of Sciences of Food Productions
via Monteroni km 7
73100 Lecce, Italy
“The model discussed by the authors is based on a simple, unifying idea that differentiation waves, based on cell cytoskeleton, i.e., contraction and expansion of the network of microfilaments and microtubules, is at the basis of mechano-transduction signalling, that brings transcription factors to regulate chromatin into specific cell-stage differentiation states, based on regulons, i.e., the wholeness of opened DNA regions and inaccessible DNA regions. Thus, from determination of a cell’s fate, i.e., signaling to advancement of process, to differentiation state, i.e., new transcriptional program and reprogramming of active regulons, clusters of cells thus divide, mature and form the various cell type component tissues of the developing embryo.”
And my favourite part:
“Overall, the book is a great book, documenting with images, schematic reproductions and drawings the embryo development, showing parallelisms, universal processes and the peculiarities of various vertebrates and invertebrates.”
You can read the full open access review here:
Igamberdiev, A.U. (2016). Book Review: Morphomechanics of Development. Lev V. Beloussov, Andrei Lipchinsky. Springer International Publ. BioSystems, In press. Web: http://www.sciencedirect.com/science/article/pii/S0303264716302532
The article is now available on line (though behind a paywall if you don’t have a university or similar library access. Here are our two favourite excerpts!
The title of the book is based on the belief of the authors that the fundamental phenomenon first described by them forms the basis for a profound explanation of the phenomenon of embryogenesis and represents a “right theory” of individual development of biological organisms. Thus the book provides an expanded explanation of this new theory of how embryos build themselves using the phenomenon of generation of differentiation waves. The background given for the theory combines simple physical principles with the most recent breakthroughs in genet- ics, biochemistry, and biophysics. Despite a huge amount of detail and experimental data, the book is accessible to a broad audience includ- ing not only embryologists but also biologists of different profiles, researchers working in many fields of science, teachers and students.
This book by Natalie and Richard Gordon represents an important development in the field of developmental biology and in the foundations of theoretical biology. Its clear presentation and style makes it a perfect complementary textbook for teaching embryogenesis and re- lated courses. It is strongly recommended to everybody who is interested in the problems of embryogenesis and, in general, in foundations of biological organization. In the end, after reading this book, we are convinced that the concept of differentiation waves explains the mystery of embryogenesis. Further elaboration and strengthening of the experimental basis of research related to the phenomenon of differentiation waves may provide new further evidence in support of this great concept.
We got our first review! Andrei Igamberdiev has reviewed our book for BioSystems. He kindly sent us an advance copy. The full review will be submitted to BioSystems and hopefully published December or January. He especially noticed and commented on how we included the Russian literature related to embryogenesis. He also praised us because the book makes embryology accessible to non biologists which we were especially pleased to hear because that was our main reason for writing. We are delighted to have someone completely independent from us say such nice stuff!
I have read your book with great interest! You convinced me that the
concept of differentiation waves is a real basis of the phenomenon
of embryogenesis. Also your book contains a lot of important
information on different aspects of not only embryogenesis but of
the whole field of general and theoretical biology.
Maybe they saw the Walmart price because they marked it down.